Translational Medicine: Are we Ready for the Prime Time?

Cancer Biomarkers: Are We Ready for the Prime Time?

A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. In cancer, a biomarker refers to a substance or process that is indicative of the presence of cancer in the body. A biomarker might be either a molecule secreted by a tumor or it can be a specific...

1 Evaluating School Performance : Are We Ready for Prime Time ?

Noninvasive Electrocardiographic Mapping: Are We Ready for Prime Time?

N oninvasive electrocardiographic imaging through body surface potential (BSP) mapping and mathematical inverse procedures represents a novel and emerging technology that enables estimation of myocardial depolarization and repolarization. As such, this mapping approach offers the possibility of not only facilitating therapeutic catheter interventions for a variety of cardiac arrhythmias, but al...

Endoscopic ultrasound-guided gastroenterostomy: Are we ready for prime time?

Interventional endoscopic ultrasonography (EUS) is currently becoming the less invasive therapeutic approach for the drainage of pancreatic fluid collections, of acute cholecystitis in patients unfit for surgery and for biliary drainage after failed endoscopic retrograde cholangiopancreatography. In addition, EUS-guided gastroenterostomy (EUS-GE) has recently emerged as a feasible procedure to ...

Ready for Prime Time

Opening of the voltage-dependent Ca 2 channels permits influx of Ca across the plasma membrane, triggering diverse physiological processes. These channels are widely distributed in the cardiovascular system, constituting the main route for Ca entry essential for excitation and contraction. Ten unique 1 subunits, grouped in 3 families (CaV1, CaV2, and CaV3), that encode the low-voltage– activate...